What's the highest positive ANA that you've had

[kellyptyler]

just curious becaue mine was 1:1280, but my other test still negative....so I ask this question just because I'm curious about everyone else

[JannaLee]

Apparently my lab measures differently from yours:  Letter from Rheumy (Feb. 2010)
"The repeat of your antinuclear antibody was once again high concentration positive.  Strongly positive is considered greater than 6 and your value is 10.5."

Kelly,

Do you know how 10.5 would compare to 1:1280?  All I can tell you is this number (for me) was 6 two years ago and 8 last year and I'm indeed more ill now than I was then.

I have high positive Sjogren's A antibodies and borderline/negative Sjogren's B.

Sending you wishes for answers and avenues to wellness!
Janna

[lynnmarie219]

Mine has been tested two times...both of them coming out 1:640 which is one level below yours.

This test gets documented in increments that are doubled as it is titrated to show how much the blood can be diluted before the antibody can no longer be detected. 

For example ( I think these are the right numbers)....1:80, 1:160, 1:320, 1:640, 1:1280 with the higher titers being positive.

[beautifulkrissy026]

Mine was also 1:640, don't know what that means or what any of the other test mean.

[Bucky]

In 1999 when my PCP sent me to the Rheumy thinking I might have Lupus my ANA was 1:2560.  The Rheumy said I didn't have Lupus.  End of story.

Fast forward ten years to 2009 and I'm sent back to the Rheumy with an ANA once again of 1:2560 as the dry eyes and mouth kick into high gear, I get a positive Primary Sjogren's Diagnose.

Bucky

[Babs659]

Mine has been tested several times.  It was 1:1280 the first time then 1:640 and a few negatives sprinkled in.  The pattern is homogenous which is typical for Lupus, but I don't meet the criteria.  That's why the rheumy dx Sjs even though the SSA, SSB and all else was negative (except thyroid AB's).

[gurs]

my highest was 1:2560 last year, shortly after my Rituxan infusion..go figure? usually, its 1:640, or 1:1280..Ive been diagnosed with primary SS, lupus overlapp,
Raynauds, possible some scleroderma?

[mac]

Janna,
You must be right about the labs testing differently.  My lab says <40 is normal and mine was 10240 with no colons in that figure.  No one did an SS-A or SS-B yet...what ever they might mean.

[louise]

My last blood work said my ANA index value was 17.05 H the reference range was <=10.00 not sure what any of that means but the rheumatologist said it is high.

[inga]

Mine is >1:1280, for ANA.  ENA is negative.  I stay very high, have for years....dropped to 640 a bit....mostly 1280 speckled/nucleolar.....or 640 only nucleolar.

On ANA Elisa, I was 2.57, cut off for + was 0.9, which meant I was extremely +.  ANA Elisa is very accurate, but not specific.  They can't seem to find the specific autoantibody.  I have severe neuropathy with my + ANA.

I meet ALL SjS criteria full blown, but, for blood work, so, I don't know what I have, really.  I am freaking sick, that is all I can say....disabled from this....looks and feels like MS, with all the accoutraments of autoimmune disease to boot.

I need a prosthetic body or a zombie body....any ideas any one?

[inga]

Make that an avatar.....skip the tail....it would get wet in the toilet...

[Patze]

Sorry folks, you know that there had to be someone to rain on the "topic"  !  Nope, never had a positive ANA or anything for that matter, sad, but true.


Patze

[inga]

Oh, one more thing, some labs do not dilute over 1:1,280.  In my area, no one goes past that....they tell me that is high enough.

Also they don't like to keep doing them, once you have an established diagnosis and high ANA on a few tests they don't seem to need more ANAs other than with an ENA, to try to find a specific autoantibody, which on me they can't find.

[Suzy]

1:1280 since 2007. I get it tested about once a year.

[Reanne]

Do all you asks for copies of your blood work from your doctors?  And would it be out of line to ask for it?