is there a connection??

[Ntysin]

I am such a curious soul...I am known for researching and asking soooo many questions that I can become an "expert" on the subject matter.  So, my questions for this post is about SJS and heredity.  What is the link?  Is there a link?  Could there had been someone in my family with SJS before me?  What I find so interesting is that my maternal aunt was diagnosed with MS and it won the battle over 20 years ago.  Her symptoms stated very very very similar to my experience...(can you say scared).  I am now learning as much about SJS as I can so I can educate my family. 

Any and all input if welcomed...

[beautifulkrissy026]

I know when I went to the rheumy one of the questions is if any of your close relatives have an autoimmune disease? Supposedly it makes you more suseptible to it if your mom or something did. I don't know anybody in my family with anything like this. I think that it is alot easier to diagnose SJS now then what it was say 10-20 years ago so alot of our family members may not have ever got a diagnosis. I dunno it makes you wonder though.
Kristine

[Scottietottie]

Hi Ntysin 

There doesn't seem to be an SjS gene as such (although I believe research in ongoing) but there seems to be a hereditary component to AI diseases. Some families seem to have a propensity for developing AI diseases - though not necessarily the same one.

I feel my kids are 'doomed'    because I now know they have AI diseases on both sides of the family. (At least they know to tell their doctors) I don't have a family medical history because my mother was adopted and my father disowned his family before he got married and would never speak about them. Neither of my parents had AI diseases to my knowledge.

My mother in law had thyroiditis, pernicious anaemia and osteoporosis. Both her daughters now have the same thing. Her mother had rheumatoid arthritis. My husband developed proriasis. My oldest son developed Crohn's las year. My oldest daughter has something weird going on with her skin that so far no dermatologist has got to the bottom of and she also gets arthritis, so I think that'll turn out to be AI eventually.

Both my siblings seem to have escaped anything as yet.

Take care - Scottie