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Salagen vs. Evoxac

Started by Sharon, August 19, 2017, 03:27:20 PM

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Sharon

How do you find Salagen and Evoxac compare in terms of:
1- Tear production
2- Saliva production
3- Length of action
4- Side effects

Thanks!

Sjogren's (+ RA): positive ANA, RNP, RNP-A, APCA. Severe eye dryness + inflammation, multiple sensitivities and allergic reactions, fatigue. 
ORENCIA, Restasis, Anti-inflammatory diet, Vit. D & C, Ubiquinol 100mg, Omega 3....

Pete0211

1 - neither gave any noticeable effect.
2 - Salagen created too much saliva production when it worked. Evoxac is more of a natural feel. I have started noticing more saliva production while I sleep (leading to wet pillows), so I might try 2xday rahter than 3xday.
3 - Salagen is quick. About two and a half hours worth of over-effectiveness, then dryness until the next dose (was taking 7.5mg x 4 / day). I never had a problem waking in the middle of the night (due to dryness) to take that pill. I'm taking one Evoxac ~every 8 hours - and it seems effective for those 8 hours. No more waking up at night :)
4 - Salagen seemed to give me the sweats, especially at night when sleeping. I haven't noticed anything with Evoxac.
Male 49 y/o; Undergoing Primary SJS diagnosis process; Cevimeline, Ubiquinol, Restasis

Sharon

Thanks Pete, Salagen gives me the sweats too.
Sjogren's (+ RA): positive ANA, RNP, RNP-A, APCA. Severe eye dryness + inflammation, multiple sensitivities and allergic reactions, fatigue. 
ORENCIA, Restasis, Anti-inflammatory diet, Vit. D & C, Ubiquinol 100mg, Omega 3....

Josie

I have not taken salagen in years, in fact, ever since I got to take Evoxac. I take the generic.
Both helped me in tears and overall dryness.
Salagen works fast and stops in an hour or 2, leaving me dry for a couple hours until I take the next one. That up and down drove me crazy! The Evoxac generic is as Pete said, more natural, and lasts for about 6 hours doing well, then drops off. I take it 3 times a day, 7:30, 2 or so, and 9 or so and it does well. If I forget it a couple hours late boy do I know, dry eyes and mouth etc, and it takes awhile to "catch up" again.

Josie

Sharon

Thanks Josie, do you feel that these meds may actually make
the dryness even WORSE when they wear off?
I don't have access to Evoxac, but when the Salagen wears off
I feel dryer than I did before taking it...
Sjogren's (+ RA): positive ANA, RNP, RNP-A, APCA. Severe eye dryness + inflammation, multiple sensitivities and allergic reactions, fatigue. 
ORENCIA, Restasis, Anti-inflammatory diet, Vit. D & C, Ubiquinol 100mg, Omega 3....