CRP going UP...

[anabanana]

So my rheumy called today and my CRP is 12.
She's not sure what to make of it, but it certainly explains why I have been feeling crappier in the last 6 weeks, everything worse, muscle weakness, tightness, strange sensory stuff like buzzing and jabbing, increased muscle twitching, stinging/burning hands and feet, and really bad dryness....

I have not been "sick" with anything, so theres no reason for it. I am concerned, as it has never been that high, on other times I've tested, 9 at most.

For comparison to myself who has SOMETHING for over 2 years, and no name yet:
My husbands CRP was .50, so low, he is healthy(but eats, drinks what he wants and does not worry about germs). After seeing his results, it really makes me realize something is serious because this is chronically elevated. Not that I didn't think it wasn't serious, but after seeing what a normal persons crp is, its an eye opener. It has meaning...

Again, negative sjogrens ab, despite worsening dryness...Waiting for ana results...something was also off with my kidney function, but didn't get exact numbers because we didn't speak, but my urinalysis was completely normal...
I felt something was up, when I did this last batch of labs.

[finallyadx]

So sorry to hear you feel so lousy anabana - this really stinks.  Sounds like you have some strange labs for sure...but it also sounds like you have some medical professionals who are trying to sort through it all. 

I saw on another post that someone had mentioned MG for you...have they tested you for this yet?  You certainly exhibit many symptoms of the disease, but then again, based on other posts I have seen from you, you exhibit so many of the sjs symptoms. 

Although your bloodwork for sjs is negative (is that correct)?  are you being treated with plaquenil anyway? I know there are rheumys who believe that sjs does not always show up in bloodwork and will treat based on the symptoms.

I, too, suffer from symptoms similar to yours and at this time, anyway, they can find nothing else other than the sjs.  I have "jabbing, stinging, buzzing", I also have tingling and numbness and most recently what I refer to as "hotness and feelings of vibrations" in my hands and feet.  I had the nerve conduction tests along with a spinal and MRI's because awhile ago they thought I had MS...unfortunately with autoimmune ANYTHING can go, symptoms can be different from one person to the next and some folks never exhibit any symptoms and things just "show up" in their bloodwork.

Whatever you do, keep with the appointments and tests they are ordering for you and I will pray that you can find some answers and resolution.  Not knowing is so very hard, once you know what you have to deal with, it is slightly easier in that you can begin to try different treatments to see what may or may not work for you.

Keep your chin up and keep us posted.

[anabanana]

Thanks finallyadx...
Yes, neg SJ ab...
Ive only had ACH and repetitive nerve stimulation, for the MG, both didn't give answers.
I will be pushing for more MG antibody labs and the single fiber emg....if docs are going to be a pain in the behind about it, I will pull out the percentage stats on MG and tests associated with it.
It shows that ALL the tests need to be run, if the initial 2 I've had don't give answers.

So your nerve conductions are normal, mine too.
How is it that we can have so much sensory nerve stuff, and this test isn't showing anything, the sensory portion?
It proves that it is not that sensitive, and that perhaps our illness is affecting the nerves from a different source, like vascular(blood vessels, circulation impairment by the inflammation), which causes the sensory nerves to be irritated, malfunction, causing the sensations and numbness we feel. I would like to argue the same argument for the motor nerve conduction, perhaps the motor nerves are irritated from inflammation in blood vessels, and therefore the result can be twitching in the muscles (again, inflammation of the circulatory/vessel system)...its my theory, and I find it very possible, since the electro studies are not proving anything...

I agree with you too, that other side of my condition sounds very much like SJ. My most recent Schirmers test said, barely any tears its systemic, thats for sure...i get the hotness in my skin of palms, and i get random hot spots in my legs mostly..., in addition to the vibrations in my arms/hands, leg/feet..

I am starting generic plaquenil today...