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Evoxac bad experience so far :*(

Started by wisconsin41, September 04, 2013, 06:42:01 AM

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wisconsin41

Hi folks,
    I started Evoxac generic last Friday night Aug. 30th. I was prescribed the standard 3x/day. Knowing that I often am sensitive to medication/supplements I took only 1 Friday night.
       1st pill: Saliva,sinuses, throat felt great and I didn't feel any side effects until the next morning. All day Sat. I felt really light-headed. I finally cleared up 24 hours after taking the 1st pill.
       2nd pill:  Sunday morning I took my 2nd pill. Felt good no side effects until about 8 hours afterward. Heart rate went up, felt like my heart was going to jump out of my chest. Went to bed with no pill. Monday morning 24hrs. after taking my last pill I woke up extremely light headed! I told my wife I thought I was going to faint. This horrible feeling lasted until the late afternoon! There was a few moments I was confused and had a hard time consentrating :'( I didn't feel better until 33 hours after my last pill was taken.   Aghhhh
       3rd pill I tried to take half at night and half in the morning. Same thing, light headed and I almost felt like I was losing my mind...

Honestly I am afraid to take any more, not sure what I will do now. I can't live with a dry sinus and gum in my mouth all the time.
Eyes:Restasis,Alrex; Plaquenil,Evoxac(sort of), Nexium, Zolpidem, Naproxen

Nancy60

Hi and sorry you're having such a hard time with Evaxac. Have you called your doctor this week to let him know?  I'm not sure about the reaction you had, it was delayed from when you took the med and Evoxac usually starts working pretty quickly and it's effects wear off fast ( that's why we take it 3 times a day). But if you are having side effects like that and your sure its the med, I would stop taking it.

On a side note, meds that come in capsule form shouldn't be split as it isnt a hard tablet. Always check with your doctor or pharmacist before splitting a medication. 

Let us know what your doctor says.

Nancy

wisconsin41

Hi,
   I am positive it is from the Cevimeline.   I didn't anticipate having side effects 24+ hours after taking it though...
Eyes:Restasis,Alrex; Plaquenil,Evoxac(sort of), Nexium, Zolpidem, Naproxen

Joe S.

I want to suggest that you do a search for the medication name and Side effects, then interactions, then counterindications.
bkn C4 & C5, herniation's 7 n, 5 t, 4 l, Nerve Damage
Lisinopril, Amlodipine, Pantoprazole, Metformin, Furosemide, Glimepiride,
Centrum Silver, Cinnamon, Magnesium, Flaxseed, Inositol, D3, ALA, ALC, Aleve, cistanche
Reiki, reflexology, meditation, electro-herbalism

wisconsin41

The ENT wrote a prescription for Pilocarpine. Can I expect the same result? Everyone is so different...
Eyes:Restasis,Alrex; Plaquenil,Evoxac(sort of), Nexium, Zolpidem, Naproxen

wisconsin41

Took a half pilocarpine, hope I don't get sick and that it works...
Eyes:Restasis,Alrex; Plaquenil,Evoxac(sort of), Nexium, Zolpidem, Naproxen

quietdynamics

#6
Hoping the pilocarpine works for you, I just re-started it.
I always introduce (wean onto) new med @ night. One medical professional recommended this so any side-effects that may be transient as the level builds and our bodies become tolerant occur at night.

Pilocarpine: When husband was researching this drug for Pharma/ Alzheimer patients...it helped with mental acuity/alertness. Unfortunately, it did not meet the study objective...but...

LOL... he better watch out.

Light and Glare...
"In ophthalmology, pilocarpine is also used to reduce the possibility of glare at night from lights when the patient has undergone implantation of phakic intraocular lenses; the use of pilocarpine would reduce the size of the pupils, relieving these symptoms. The most common concentration for this use is pilocarpine 1%, the weakest concentration."
Sjogrens ANA 1:640; SS-A/B+; Fibro; IBS; Neuro symptoms,Thyroid Anti-bodies; Ocular Rosacea, Livedo reticularis,

"You can't have a positive life with a  negative mind"

eye2dry

I took pilocarpine for a few days back in 2011. I did not have a

good experience with it.  I got severe vertigo with nausea and vomiting.

Had to see my GP who gave me a injection of Compazine/or Phenergan (can't remember)

plus a RX for meclizine and Valium.

I had vertigo so bad it felt like the room was being picked up and laid on it's side.


But shortly after taking a pilocarpine I got a burst of saliva...which shows it worked for me.


eye2dry
medications: synthroid- meloxicam- plaquenil- lots of supplements

***Lord help me to be the person my dog thinks I am***

wisconsin41

Wow eye2dry! Did that happen later or near the time you swallowed it?
Eyes:Restasis,Alrex; Plaquenil,Evoxac(sort of), Nexium, Zolpidem, Naproxen

Velcro

Everyone is different on different medications.  I started pilocarpine a week ago and haven't had any adverse reactions.

quietdynamics

Quote from: eye2dry on September 06, 2013, 08:38:28 AM
I took pilocarpine for a few days back in 2011. I did not have a
good experience with it.  I got severe vertigo with nausea and vomiting.
Had to see my GP who gave me a injection of Compazine/or Phenergan (can't remember)
plus a RX for meclizine and Valium.
I had vertigo so bad it felt like the room was being picked up and laid on it's side.
But shortly after taking a pilocarpine I got a burst of saliva...which shows it worked for me.


eye2dry

I had vertigo type dizziness and nausea for months pre- dx with Sjogrens. So without any medications.
A symptom of Sjogren? Possible, probable...in my situation.

As Velcro said " Everyone is different" that goes for symptoms as well.
Once meds have been added...discerning side effects or symptoms is very difficult.
Sjogrens ANA 1:640; SS-A/B+; Fibro; IBS; Neuro symptoms,Thyroid Anti-bodies; Ocular Rosacea, Livedo reticularis,

"You can't have a positive life with a  negative mind"

eye2dry

hi Wisconsin.

I believe I got 3 days of pills in me.

My rheumy did mot suggest I try any other similar meds.....

however, fast forward to 2013 and I don't have the dry mouth symptoms near as bad.

Also, my eyes have straightened out as well......not near as dry.

I don't know wether to be glad for it or concerned.


eye2dry
medications: synthroid- meloxicam- plaquenil- lots of supplements

***Lord help me to be the person my dog thinks I am***

BKreader

Pilocarpine did made my heart rate go up. Anxiety attack feeling along with burst of cold sweats and wierd chills, several abdominal cramp. I was prescribed up to 3x a day but didn't do that do to side effects.

Evoxac is pretty good. I take the name brand ones. I am working on adjusting my amount. I was prescribed 2 a day, but after a few days it seems to build up in my system causing my minor salivary ducts to swell and very painful at the openngs. I also developed a nasty taste in my mouth. I now take only one every other day. It still seems to help, but my eyes feel quite a bit drier. I also earned how to massage my saliva ducts in he morning to clear out thicker saliva that builds up during the night. My ducts have been feeling better and no more weird nasty taste.

Bad heart rate stuff sucks and can be scary. I hate trying new meds.

Good luck you may need to play around with different treatments. There are many products the can help symptoms.
Primary Lupus, secondary atypical Sjogren's, Recurring episcleritis, Esophageal spasms, Hashimoto's, GERD, Perioral Dermatitis
Levothyroxine, Liothyronine Sodium, Plaquinil, Prilosec
Salmon oil, Flax oil, Restasis, Tears Naturale

mistyrain

#13
Hi Wisconsin: I searched for information on Evoxac on the sjworld forum and found some interesting posts on  a thread in 2008 as follows:


Author Topic: Evoxac--heart problems  (Read 2139 times)
abner
Guest

Evoxac--heart problems

on: July 13, 2008, 08:06:05 PM


You might like to read the posts and can access it by typing in the search   -  evoxac and heart

Hope this might be helpful
Edith

bjnc

To look at side effects of meds, I look at the sites about the drug, but also look at askapatient.com. 

It has actual patient reviews where they rate the drug, put in side effects and comments for each drug, as well as the date they rated it and their age.  I've found it to be very helpful to see if people experience a side effect that is listed in the literature.

Evoxac is on there; you might want to look at it.
Female 56, diagnosed with Psoriatic Arthritis 1986; also have Undifferentiated Connective Tissue Disease (in my case, a combination of Lupus and Sjogren's), Grave's Disease. Remicade, (a biologic for Ps. Arthritis), Arava, Cymbalta, Evoxac, Trazodone, Synthroid; Miralax