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Gene therapy "corrects SJS"

Started by Sharon, December 03, 2017, 12:51:44 PM

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Sharon

I just want to give a stage to this amazing study that could potentially even "cure" Sjogren's Syndrome in some sufferers:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878512/

Unfortunately it has yet to be picked up for further research funding.

Sjogren's (+ RA): positive ANA, RNP, RNP-A, APCA. Severe eye dryness + inflammation, multiple sensitivities and allergic reactions, fatigue. 
ORENCIA, Restasis, Anti-inflammatory diet, Vit. D & C, Ubiquinol 100mg, Omega 3....

WhatYouSjo

Thanks for posting this Sharon. There are a lot of hurdles to jump in order to get from mouse trials to a successful human product, but it's always good to have such promising options. It's interesting that they found that systematic inflammation was also resolved with this therapy; if nothing else, it will hopefully help advance our understanding of the underlying mechanisms of SS.
Seronegative male diagnosed 2014. Using generic Plaquenil, Restasis, Xiidra, low-carb diet, moderate exercise, select supplements, helminthic therapy, & LDN. My treatment regimen

My website has posts on research and news.

Sharon

My thoughts exactly WhatYouSjo.
Their findings of a correlation between water permeability dysfunction and systemic inflammation
are a breakthrough.
Sjogren's (+ RA): positive ANA, RNP, RNP-A, APCA. Severe eye dryness + inflammation, multiple sensitivities and allergic reactions, fatigue. 
ORENCIA, Restasis, Anti-inflammatory diet, Vit. D & C, Ubiquinol 100mg, Omega 3....

CureSjogrensNow


Sharon

I'm not sure how that's done, but I would be willing to contribute towards its development.
Maybe get the Sjogren's Syndrome Foundation involved?

Sjogren's (+ RA): positive ANA, RNP, RNP-A, APCA. Severe eye dryness + inflammation, multiple sensitivities and allergic reactions, fatigue. 
ORENCIA, Restasis, Anti-inflammatory diet, Vit. D & C, Ubiquinol 100mg, Omega 3....

CureSjogrensNow

I will try and contact them and see what the hold up is? And a potential budget?