One yr in review 2016: Sjogren's (article) and other research.

[quietdynamics]

So much information in this 11 page review.. whew. I have included some of the research I did to better, somewhat wrap my head around some of the points that applied/interested me.
Really enjoyed the discussion of SJS patient subsets, need for early Dx. Really I am going to read a few more times, have DH read and save.
Hope this opens up discussion ...

One year in review 2016: Sjögren's syndrome

ABSTRACT
Sjögren's syndrome (SS) is a complex
heterogeneous disease charactered by
a broad spectrum of clinical and serological
manifestations, including nonHodgkin's
lymphoma (NHL).
Last year, 2015, was an exciting year for research into SS with novel insights into disease pathogenesis, clinical
aspects and long-term outcomes. In addition, the use of biologic therapy in SS is rapidly expanding, with new
evidence emerging regarding potential therapeutic targets. In this article, we will provide an overview of the recent
literature on the pathogenesis, clinical features and novel treatments of SS.
http://www.clinexprheumatol.org/article.asp?a=10452  Full review

ACR: New Sjögren's classification criteria on the way
http://www.rheumatologynews.com/specialty-focus/lupusconnective-tissue-diseases/single-article-page/acr-new-sjoegrens-classification-criteria-on-the-way/2bb6a303f818523beea4c5fa3b268d87.html

Alexithymia /?e?l?ks???a?mi?/ is a personality construct characterized by the sub-clinical inability to identify and describe emotions in the self.
Asthenia vs. myasthenia. Asthenia (Greek: ??, lit. lack of strength but also disease) is a medical term referring to a condition in which the body lacks or has lost strength either as a whole or in any of its parts. It denotes symptoms of physical weakness and loss of strength.
methylation DNA methylation is an epigenetic mechanism used by cells to control gene expression. A number of mechanisms exist to control gene expression in eukaryotes, but DNA methylation is a commonly used epigenetic signaling tool that can fix genes in the "off" position.Sep 17, 2015

Vasculitis in Sjogren's Syndrome  http://info.sjogrens.org/conquering-sjogrens/bid/123193/Vasculitis-in-Sjogren-s-Syndrome
http://www.wikiwand.com/en/Cutaneous_small-vessel_vasculitis

T Follicular Helper (Tfh) Cells https://www.rndsystems.com/research-area/t-follicular-helper--tfh--cells

EULAR Sjögren's syndrome disease activity index (ESSDAI): a user guide http://rmdopen.bmj.com/content/1/1/e000022.full

Systemic lupus erythematosus and primary fibromyalgia can be distinguished by testing for cell-bound complement activation
products http://lupus.bmj.com/content/3/1/e000127.short?g=w_lupus_current_tab

Hypergammaglobulinaemia and autoimmune rheumatic diseases http://ard.bmj.com/content/51/11/1185.full.pdf

A Preliminary Study on the Relationship between Platelet Serotonin Transporter Functionality, Depression, and Fatigue in Patients with Untreated Chronic Hepatitis C  http://www.hindawi.com/journals/drt/2014/821381/

Study finds biological basis for gastrointestinal symptoms in people with non-celiac wheat sensitivity http://www.news-medical.net/news/20160726/Study-finds-biological-basis-for-gastrointestinal-symptoms-in-people-with-non-celiac-wheat-sensitivity.aspx

SJS Video *When a person is diagnosed with Sjögren's, they often don't know where to begin. http://info.sjogrens.org/conquering-sjogrens/bid/157379/Recently-Diagnosed-with-Sjogren-s-Here-s-a-Place-to-Begin

Best to all ~.~

[warmwaters]

Thanks, your notes will keep me reading for the next few days  .  I usually only read one at time, as most of the medical articles are so densely packed.

[Jasper]

Thanks so much for posting these links.

The articles all look very interesting and I intend to read all of the them.