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Article - Neurological Disorders in Primary Sjögren's Syndrome

Started by LittleBlue, April 29, 2013, 05:20:01 AM

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LittleBlue

http://www.hindawi.com/journals/ad/2012/645967/

"6. Biological Markers in Patients with pSS and Neurological Manifestations
Anti-Ro and anti-La seem to be less frequent in pSS patients with neurological involvement (40%) compared to patients without neurological manifestations (60% of positivity). Thus, new markers are necessary in pSS to better classify subpopulations of patients with neurological involvement. Some antibodies have been described as potential serological markers of neurological involvement in pSS. However, their useful application is doubtful. IgA and/or IgG anti-alpha-fodrin antibodies in pSS appear to be common in neurological pSS (64.5% of 31?pSS patients with neurological manifestations) [80]. However, this percentage was not different from pSS patients without neurological manifestations."


LittleBlue