What is seropositive exactly

[Tivia]

I know I should know this, but for some reason I cant think. Is seropositive just a positive ANA or is it ANA + ssb ssro ssla. I dont have the + ss antibodies as of my last test in September, but my ANA was high and my IGa was high. Does that mean sero+ or sero-...why cant I remember this stuff lol

[Chrisb]

Hi Tivia
I have the opposite question 

What does zero negative mean? LOL!  I see so many people posting that?

[Tivia]

I really cant find if just positive ANA with a pattern means seropositive, or if thats seronegative. I dont think my doc did a lot of test I see ss antibody tests and IG tests and complement along with the ANA. I hope someone can answer what means sero+

[MaryBee7]

I thought "seronegative" meant no la or ro antibodies.  And that ANA is broader...not exclusive to SjS.  Could be and likely am...wrong!   

[mshistory]

SS-A isn't exclusive to Sjogren's either though. It's also commonly found in SLE patients, particularly those with photosensitivity and skin issues (like me).

I always thought sero-negative meant that all blood work is normal but I guess we all have different uses of sero-negative/positive!

[Iris]

My doc considers me sero negative with a positive ANA and negative anti-Ro/SSA, anti-La/SSB..