Sjogrens World Forums

Sjogrens Topics => Living With Sjogren's => Topic started by: TTSandy on January 02, 2019, 09:42:21 AM

Title: Domperidone
Post by: TTSandy on January 02, 2019, 09:42:21 AM
I have been following the boards for some time but have not posted to date.  I have a questions about Domperidone which has been a life saver form some here. My question is are you taking this drug along with Plaquinel, as I have seen that it is contraindicated if taking Plaquinel (actually it says hydroxychloroquine which is the generic form.
Thanks.
Title: Re: Domperidone
Post by: rnathans on January 02, 2019, 07:32:47 PM
I have been taking both for years. Do they say why it is contraindicated?
Title: Re: Domperidone
Post by: TTSandy on January 03, 2019, 06:15:22 AM
No they do not, it is just on a list of contraindicated drugs when taking this medication.  I was wondering because it looked like a couple other members were taking both as well.
Title: Re: Domperidone
Post by: Linda196 on January 03, 2019, 10:35:02 AM
The reason for the contraindication is that both are "QT-interval lengthening agents" which means both can have an effect on the electrical conduction and rhythm of the heart, which can be compounded when both are taken together.

If it's necessary to take both, an annual ECG will show developing problems, and any "palpitations" or irregular heart beat should be reported immediately.
Title: Re: Domperidone
Post by: TTSandy on January 03, 2019, 01:13:08 PM
Thank you for the clarification.