Sjogrens World Forums

Sjogrens Topics => Living With Sjogren's => Topic started by: Sharon on December 03, 2017, 12:51:44 PM

Title: Gene therapy "corrects SJS"
Post by: Sharon on December 03, 2017, 12:51:44 PM
I just want to give a stage to this amazing study that could potentially even "cure" Sjogren's Syndrome in some sufferers:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878512/

Unfortunately it has yet to be picked up for further research funding.

Title: Re: Gene therapy "corrects SJS"
Post by: WhatYouSjo on December 04, 2017, 08:35:49 AM
Thanks for posting this Sharon. There are a lot of hurdles to jump in order to get from mouse trials to a successful human product, but it's always good to have such promising options. It's interesting that they found that systematic inflammation was also resolved with this therapy; if nothing else, it will hopefully help advance our understanding of the underlying mechanisms of SS.
Title: Re: Gene therapy "corrects SJS"
Post by: Sharon on December 04, 2017, 03:07:40 PM
My thoughts exactly WhatYouSjo.
Their findings of a correlation between water permeability dysfunction and systemic inflammation
are a breakthrough.
Title: Re: Gene therapy "corrects SJS"
Post by: CureSjogrensNow on December 05, 2017, 10:26:58 AM
Why don't we help fund it?
Title: Re: Gene therapy "corrects SJS"
Post by: Sharon on December 05, 2017, 01:39:44 PM
I'm not sure how that's done, but I would be willing to contribute towards its development.
Maybe get the Sjogren's Syndrome Foundation involved?

Title: Re: Gene therapy "corrects SJS"
Post by: CureSjogrensNow on December 06, 2017, 03:54:30 PM
I will try and contact them and see what the hold up is? And a potential budget?