I'd like to ask, who has had testing for beta 2 microglobulin? What were the results?
My recent result was 2.70. In 2015 it was 2.56. Normal range is .7 - 1.8.
My rheumatologist told me this is common in autoimmunity and that if she refers patients to a hematologist with a level like mine, they get sent back to her. I'm curious about just how common it is and what other doctors have had to say about it.
Thanks.
I'v not actually heard of B2M in reference to immune disease, only in established blood cell diseases as a disease activity marker, or the urine levels to establish disease activity in tubular filtration disorders. Even for those, it's not used as a stand alone test or for diagnosis. If there were no other hematologically related labs out of range to use with an altered B2M level. that could explain why a hemotologist would choose not to follow a patient.
Do you know what units of measurement were used in you lab? The ranges I'm familiar with are 0-0.3 mcg/ml in urine levels , and 0-3 mcg/ml in blood serum. (mcg is sometimes written as a cursive style "u")
It's mg/L.
I searched on b2 microglobulin & Sjogren's and I see lots of papers, but I haven't read any of them yet. I'm a little afraid of finding out I'm headed towards lymphoma.
I'm not sure if I ever asked her why she ran it.
Thanks.
Yes, had this done several years ago...Mine was also high at that time...2.58 (0.70-1.80)..went to see a hematologist, and said it was prob autoimmune related? who knows?? our bodies are so not normal and they dont know what to do with us because we are so abnormal.
I dont think I had it tested again...whats the point anymore? can you tell Im frustrated by the whole medical society/autoimmune disorders?
They cant explain anything..need more research. Im interested in finding out what happens with you. I think I will ask my rheumy to run that test in a few months...im curious too.
Dont worry about the Lymphoma thing either. Just have some more testing done and see what they can find. I think my hematologist said I could do bone marrow test, but after running other labs, said didnt really indicate any type of cancer, so we let that go.
Gursie
I have not heard of that either so I can't really add anything to this.
susanep