Hi All, I am curious whether anyone has used platelet rich plasma eye drops. I have been reading about the rejuvenation characteristics of PRP in orthopedics. It would be exciting if similar results could be achieved with eye issues. :D
The Role of "Eye Platelet Rich Plasma" (E-Prp) for Wound Healing in Ophthalmology.
Blood derived products have demonstrated their capacity to enhance healing and stimulate the regeneration of different tissues and this enhancing effect is attributed to the growth factors and bioactive proteins that are synthesized and present in blood.
Eye platelet rich plasma (E-PRP) provides higher concentration of essential growth factors and cell adhesion molecules by concentrating platelets in a small volume of plasma as compared with autologous serum, the latter being used widely in ophthalmology for epithelial wound healing of the cornea for the last two decades. These growth factors and cell adhesion molecules have a major role in wound healing and enhance the physiological process at the site of the injury/surgery via eye drops or clot.
E-PRP has been used more recently, and has achieved successful outcomes in peer-review articles in the treatment of dormant ulcers (epithelial defects of the cornea that fail to heal), moderate to severe dry eye syndrome, ocular surface syndrome post Laser In Situ Keratomileusis (LASIK), and for surface reconstruction after corneal perforation associated with amniotic membrane transplantation.
Preparation of E-PRP in the two available formulations, eyedrops and clot, is inexpensive and easy although it requires following strict sterility conditions using sterile and disposable materials and operating inside a laminar flow hood.
No serious adverse effects have been described with the use of these products, and it is generally well tolerated. In summary, Platelet enriched plasma in the form obtained in ophthalmology, E-PRP, is a reliable and effective therapeutic tool to enhance epithelial wound healing in ocular surface disease.
Thanks for the info! I'm always glad to hear that something out there might help as this disease progresses. Autologous serum eye drops are working for me, but only moderately (way better than artificial tears!). I'll have to bring this up with my doctor.
I work at a vet clinic and when we have patients with horrible ulcers we take some blood, usually theirs, and make plasma eye drops. I have seen it work better than even the most expensive man made drop.
Lolo
This was posted about eye drops made from a patients own blood, used for dry eyes. It mentions the lab this rheumy orders it through. Might be helpful for those of you wanting to try this.
Nancy
http://www.sjogrensforum.com/from-the-doctor/autologous-eye-serum-for-very-dry-eye/