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Sjogrens Topics => Living With Sjogren's => Topic started by: gold55 on November 30, 2011, 05:32:22 PM

Title: Plaquenil.....does it really restore some eye and mouth moisture??
Post by: gold55 on November 30, 2011, 05:32:22 PM
Hi All,
I have one rheumatologist who says Plaquenil does improve some patient's dryness and then I have another rheumatologist who says IT DOES NOT!!!! 

With everything I've read here, all personal experiences, I would say it does restore some moisture in a lot of members taking Plaquenil. 

Why would the second rheumy (she's more experienced than the first) give me a flat out NO!  She is a D.O. so maybe she doesn't believe in treating with the stronger drugs???  Please help with your opinions!  thanks
Title: Re: Plaquenil.....does it really restore some eye and mouth moisture??
Post by: Cheryl on November 30, 2011, 05:58:42 PM
Hi Gold,
I am not aware if plaquenil has helped dryness for me.  I do think that other members have noticed improvement, though.  I wonder if its anti-inflammatory properties might be the reason for that (?)
Cheryl
Title: Re: Plaquenil.....does it really restore some eye and mouth moisture??
Post by: drylady on November 30, 2011, 06:23:43 PM

Hi Gold. I have taken generic Plaquenil since July 2010 and it has helped my dryness. It has really helped my eyes and inflammation in general.

I think it is individual what effects you'll experience from what I've read on here. I guess you'll have to try it and see what it can do for you. Personally I feel a lot

better on the drug.
Title: Re: Plaquenil.....does it really restore some eye and mouth moisture??
Post by: LouLou1981 on November 30, 2011, 08:27:49 PM
I've been taking the generic Plaquenil since May 2011. My symptoms were mild, I didn't even know anything was wrong until I had some blood work done for different reasons. My rheumy put me on it to stop the progression. All of my symptoms have gone down so much the only time I think about having SjS is when I take my meds in the morning and when I have a flare up.  Other than that it's in the back of my mind thankfully.

I know without it (due to finances I was unable to refill my Rx and didn't have any for about a 1 1/2 weeks. I KNOW, big NO NO, but we've had a rare tough time and I had to decide which was needed more - peanut butter and bread for my son for his school lunch or my meds for a few days) my symptoms come back - hair loss, dry lips, mouth, eyes and fingers.

Good luck!
Title: Re: Plaquenil.....does it really restore some eye and mouth moisture??
Post by: Sadie963 on November 30, 2011, 09:00:43 PM
I have only been on Plaquinel since last January but I do have a bit more moisture in my mouth. I'm considering starting Salagen since my rheumie mentioned trying it out on my last visit.

I don't notice any real improvement in my eyes. They are still pretty dry even with eye drops and plugs in bottom but I use a computer a lot at work too.
Title: Re: Plaquenil.....does it really restore some eye and mouth moisture??
Post by: Luna on December 01, 2011, 05:15:14 AM
I have been on Plaquenil sinse june of this year. My doctor never said it would help with dryness. and it hasn't.

Luna
Title: Re: Plaquenil.....does it really restore some eye and mouth moisture??
Post by: Jellyb on December 01, 2011, 05:46:24 AM
Hi, Gold,
My rheumy is older and seems to gave a lot of knowledge about SJS, and he told me from the get go, that plaquenil would not help with the dryness, but my eyes and sinuses are much better from the restasis, and I think my dietary changes have helped with the mouth dryness.

I think Cheryl is right about the anti inflammatory properties being a factor with the plaqenil.
Title: Re: Plaquenil.....does it really restore some eye and mouth moisture??
Post by: DragonflyC on December 01, 2011, 06:02:39 AM
They're probably both right.

Plaquenil does not have a direct impact on dryness--it doesn't encourage tear or saliva production. It does, however, lower inflammation, and if our glands are less inflamed, it only makes sense that they will function better, which may lead to less dryness.

My take on it is that plaquenil can help with dryness, but it's in a roundabout way.

Title: Re: Plaquenil.....does it really restore some eye and mouth moisture??
Post by: ohiolady on December 01, 2011, 06:22:12 AM
Both of my rheumatologist have said the studies do not show it helps with the dryness.

Anna
Title: Re: Plaquenil.....does it really restore some eye and mouth moisture??
Post by: A66eyroad on December 01, 2011, 06:49:48 AM
I don't know whether it's helped with the dryness, but I do know that Plaquenil has given me my life back. Missing as few as two days makes a difference with me.

I understand about putting your child first, though, LouLou. It's a shame that it's had to come to that.
Title: Re: Plaquenil.....does it really restore some eye and mouth moisture??
Post by: gold55 on December 01, 2011, 07:40:52 AM
thank you for all the information.....now, does anyone feel the Plaquenil has helped stop the progression of your arthritis??  Some of the SJS arthritis can be agressive and erosive from what I've read!
Title: Re: Plaquenil.....does it really restore some eye and mouth moisture??
Post by: Duchess on December 01, 2011, 10:16:27 AM
Gold55

It has helped with the joint pain and swelling I had in some fingers.

Duchess
Title: Re: Plaquenil.....does it really restore some eye and mouth moisture??
Post by: Luna on December 01, 2011, 12:39:05 PM
It helped with the inflamation and has lessoned the pain some. I still hurt, but can use my joints (hands and feet and shoulders,etc. ) my fatigue is not better though.

Luna
Title: Re: Plaquenil.....does it really restore some eye and mouth moisture??
Post by: lindaneall on December 01, 2011, 04:28:42 PM
I truly feel the Plaquenil has helped my dry mouth.  Unfortunately, it hasn't helped my dry eyes.
Title: Re: Plaquenil.....does it really restore some eye and mouth moisture??
Post by: KellyG999 on December 01, 2011, 04:41:32 PM
 :( Unfortunately it didn't help me at all. I was told there was a small chance it would help my dryness and a better chance it would help joint and bone pain. All I got was a 3 month long upset stomach. Others obviously had much better experiences than me! I sometimes think I am a martian. My body chemistry seems so different from everyone elses.

KellyG
Title: Re: Plaquenil.....does it really restore some eye and mouth moisture??
Post by: mshistory on December 01, 2011, 05:12:24 PM
Plaquenil has not helped with dryness. In fact, that continues to get worse. My eyes have actually been burning all day  :( My chronic cough continues to get worse as well.

Plaquenil has helped with the swelling in some joints, but hasn't completely gotten rid of the joint pain (particularly knees) and has not helped with fatigue at all.