I don't if my body has adjusted and become accustomed to 400 mg of Plaquenil, but my feet and ankles hurt constantly like they did before starting it. : (
How long have you been on Plaquenil? It often takes months to work. Also you might ask your dr about anything else you could take (in addition) or not.
I take methotrexate plus Plaq and some others. Lucy
I've been on the plaquenil for years. It was working now I am not sure it is helping much.