Author Topic: Controversy over the Safety of Melatonin in Autoimmune Diseases  (Read 18500 times)

Carolina

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Dear Sjogies:


Last night my husband (PhD biologist who has done research in transplantation immunology and taught at a medical school for 25 years) asked me if I was still taking melatonin at night.

I've been taking it for YEARS, probably at least 20.  And I was still taking it.

He said, you know it strengthens your immune system, and might not be good for you, with your autoimmune problems.

I did some research and he's right.   So the melatonin came out of my sorted pill boxes immediately.

The odd thing is that in almost every OTHER circumstance improving your immune system is a good thing!  and melatonin does lots of really great stuff.  But no longer for me.

Here is one part of an article published by Vanderbilt University

http://www.vanderbilt.edu/AnS/psychology/health_psychology/melatonin.htm#Conclusions%20on%20Melatonin


Is melatonin safe? Melatonin is one of the least toxic substances known . The only side effects related with taking a large amount of melatonin are continued drowsiness and a slower reaction time  . Many people are discouraged from taking melatonin. People with the symptoms of severe mental illness, severe allergies, auto-immune diseases, or immune system cancers such as leukemia should not be taking melatonin. It is also not recommended during pregnancy or for women who want to conceive. There have not been many significant studies done with this drug. While it appears to be safe, melatonin has not yet been approved by the Food and Drug Administration.

This seems to me to be an endless process of learning.

Kisses

Carolina
« Last Edit: June 13, 2010, 07:09:36 AM by Carolina »
Female-Elaine,79-CVID-pSJS-WMD (Eylea) Inter.
Cys-PN-CAD-Osteoarth-SFN-Oral Lichen Planus-SIBO-Act.Purpura-Tinitus-Meniere's-Hearing Loss-Achalasia-Hand Surgeries, UTI's-Braces/Walker-IVIG Gamx-Medrol-Gabapentin-Atenolol-Pilocarpine-LDN-Nasonex-Lipitor-Estrogel-D-Mannose-NAC-Om.3-Methotrexate-Esome

Epson

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Re: Controversy over the Safety of Melatonin in Autoimmune Diseases
« Reply #1 on: June 13, 2010, 09:28:48 AM »
That's good to know, I take it because the sleep clinic told me to, but I never found that it made any changes in my quality of sleep.

sewandsew

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Re: Controversy over the Safety of Melatonin in Autoimmune Diseases
« Reply #2 on: June 13, 2010, 10:28:07 AM »
Good info!  Who would have thought?  Thx for posting.

Patze

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Re: Controversy over the Safety of Melatonin in Autoimmune Diseases
« Reply #3 on: June 13, 2010, 02:14:25 PM »
Egads, what else can't we use? 


Patze
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Carolina

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Re: Controversy over the Safety of Melatonin in Autoimmune Diseases
« Reply #4 on: June 13, 2010, 03:07:45 PM »
Yeah, Patze,

and it's a miracle substance for everyone else.

Go figure.

He just told me last night.

He thought it over and came up with the idea.

What a guy. 

and he was right it turns out.

I wonder how I'll sleep tonight?

Oh well, let's find out.

kisses

Carolina
Female-Elaine,79-CVID-pSJS-WMD (Eylea) Inter.
Cys-PN-CAD-Osteoarth-SFN-Oral Lichen Planus-SIBO-Act.Purpura-Tinitus-Meniere's-Hearing Loss-Achalasia-Hand Surgeries, UTI's-Braces/Walker-IVIG Gamx-Medrol-Gabapentin-Atenolol-Pilocarpine-LDN-Nasonex-Lipitor-Estrogel-D-Mannose-NAC-Om.3-Methotrexate-Esome

Madderakka

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Re: Controversy over the Safety of Melatonin in Autoimmune Diseases
« Reply #5 on: June 13, 2010, 03:12:04 PM »
Great. I have been using that for almost a year because I have sleep problems. Thanks for the info.

Blue Kat

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Re: Controversy over the Safety of Melatonin in Autoimmune Diseases
« Reply #6 on: June 13, 2010, 03:46:08 PM »
Thanks for the info.  I tried taking it for a while some time ago in the hopes that it would help me sleep, but it never did so I stopped taking it.

ohiolady

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Re: Controversy over the Safety of Melatonin in Autoimmune Diseases
« Reply #7 on: June 13, 2010, 04:07:40 PM »
You know I did know this because it was listed on the bottle.  People with autoimmune illness should not use.

Anna
SJS  Hashimoto's   Mild Raynauds  GERD  Gastroparesis
Restasis, Evoxac, Dexilant,  Domperidone, Zofran and Synthroid. Fish Oil, Vit D and B12  R lipoic acid,  Acetyl L Cartnine, Vitamin B1, and The Perfect Food Green and Fruit supplement

Kidney Cancer Survivor   
Female   Age: 62

Carolina

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Re: Controversy over the Safety of Melatonin in Autoimmune Diseases
« Reply #8 on: June 13, 2010, 04:21:26 PM »
OMG Anna
do you think I've ever read the bottle?
sigh

so obvious and so NOT ME.

When all ELSE fail, read directions.

I never read directions.

I  need others to read the directions and tell me.

Soooooo lacking in common sense

OK, I checked,  It's NOT on my bottle.  WHEW.

But I haven't ever read any bottle in 20 years, I must admit.

Carolina
« Last Edit: June 13, 2010, 05:03:08 PM by Carolina »
Female-Elaine,79-CVID-pSJS-WMD (Eylea) Inter.
Cys-PN-CAD-Osteoarth-SFN-Oral Lichen Planus-SIBO-Act.Purpura-Tinitus-Meniere's-Hearing Loss-Achalasia-Hand Surgeries, UTI's-Braces/Walker-IVIG Gamx-Medrol-Gabapentin-Atenolol-Pilocarpine-LDN-Nasonex-Lipitor-Estrogel-D-Mannose-NAC-Om.3-Methotrexate-Esome

Madderakka

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Re: Controversy over the Safety of Melatonin in Autoimmune Diseases
« Reply #9 on: June 13, 2010, 05:01:16 PM »
It's on the bottle? I feel like an idiot now.  ::)

malditogrillo

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Re: Controversy over the Safety of Melatonin in Autoimmune Diseases
« Reply #10 on: June 13, 2010, 07:26:09 PM »
i used to take it and i stopped whenever i broke out in hives and my face became swollen and was blessed with horrible esophageal spasms one weekend.   they didnt know what caused it, so i just stopped taking everything  i had been at the time.   makes sense tho.

BonusMom

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Re: Controversy over the Safety of Melatonin in Autoimmune Diseases
« Reply #11 on: June 13, 2010, 11:28:46 PM »
Fabulous info-thanks so much for sharing.  Would you mind if I posted this on a Lupus forum I belong to? I believe many Lupus members are unaware of the issues netween melatonin and AI issues, just like the number of Sjoggies that were uninformed....

LeoLady

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Re: Controversy over the Safety of Melatonin in Autoimmune Diseases
« Reply #12 on: June 14, 2010, 01:01:07 AM »
Carolina:

Thanks for posting.  My sister has been urging me for years to take melatonin as it really helps her sleep.  I kept declining because I take Trazadone as a sleep-aid.  Turns out I made the right choice and didn't even know it.

LeoLady

Patze

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Re: Controversy over the Safety of Melatonin in Autoimmune Diseases
« Reply #13 on: June 14, 2010, 03:04:06 AM »
How did you sleep Carolina?


Patze
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Blue Kat

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Re: Controversy over the Safety of Melatonin in Autoimmune Diseases
« Reply #14 on: June 14, 2010, 05:51:59 PM »
In my own defense, I took it before I knew I had an autoimmune disorder.