Author Topic: Clindomycin & C. Diff  (Read 430 times)

Judie P

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Clindomycin & C. Diff
« on: April 03, 2019, 03:48:59 PM »
I do not profess to be a doctor or tell anyone what they should do, but I feel it is important for Sjogren's people to know my story and heed warning.  Seven weeks ago, I developed quite a nasty rash and then it turned into a wound.  I finally went to ER and they told me that it was MRSA.  They gave me three antiobiotics (Clindomycin & Bactrim) to help it heal, becuase I was pre-diabetic and had Primary Sjogrens.  The next day I had a nurse practitioner appointment who told me it was a spider bite and keep taking the antibiotics.  I did so for 10 days.  On the final day, there was a pimple under my arm that began to turn into what looked like another MRSA patch.  After four days being off the antiobiotics, I had a bout of diarrhea, which only last one day.  However, I was wiped out and felt warm.  No fever, so I figured it was residue from the antiobiotics.  this past weekend, all signs of diarrhea were coming back and by Sunday, I not only had loose stools but a ton of bloody discharge.  Time to go back to ER.  After waiting 15 HOURS in the ER waiting room, the ER doc saw my at 4:30AM.  I had the intelligence to bring samples of my stool and the bloody discharge on the toilet paper.  She looked at the large pimple first and said, "Yup, that is another patch of MRSA."  She took the samples to the lab, hoping they could still use them after 18 hours.  Her guess was that I had C. Diff.  My blood work and urine samples came back fine.  However, the next day I got a call from the Advice Nurse and the ER doctor that my stool tested very positive for C. Diff.  C. Diff is a very dangerous infection of the large intestines (and colon) that causes inflammation and affects the soft tissue that begins to bleed and create a lot of pus.  It can be fatal.  I am hoping that this new round of antibiotic (Flagil) will do the trick, but in the meantime I have a low grade fever, painful intestinal issues, and feel lethargic.  It has put a stop to any momentum I did have.

I tell you this because should you have diarrhea for several days after taking a round of strong antibiotics, and you see blood or discharge, PLEASE go to ER or get a same day appointment with your doctor.  The longer you wait, the more chances of it turning into surgery or death.

Hoping everyone stays well.
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Carolina

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Re: Clindomycin & C. Diff
« Reply #1 on: April 03, 2019, 04:42:16 PM »
Dearest Judie P,

You are experiencing such a terrible nightmare.  My heart goes out to you.  Any infection is exhausting and antibiotics have their own effects on us.

Please rest, get better, and be kind to yourself.

And keep us posted, daily.

Hugs, Elaine

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Skylar

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Re: Clindomycin & C. Diff
« Reply #2 on: April 03, 2019, 06:32:38 PM »
OMG Judie P, what a dangerous nightmare you are going through. I hope you are being seen at a excellent hospital that is up to date with the best treatment for C. Diff. and MRSA. Are you being seen by specialists who deal with these serious infections?

My daughter's mother-in-law died last year from C. Diff. She was in her 60's and otherwise in good health until the dentist had put her on antibiotics for an extended time for a tooth abscess.

I hope you are being treated by a hospital that are prepared to treat you with the most up to date and preferred therapy (usually a fecal transplant). The reason this poor woman died was because she wasn't. Makes me angry when I think of it and her loss.

OTOH I have a good friend who had it last year - and she was at a well regarded teaching hospital. It took a toll on her physically, she's still walking with a walker because she never fully gained back her muscle lose. But she survived and recovered fairly quickly. I've also known several other people who fully recovered and I hope you are one of those.

Do take extra special care of yourself.


Joe S.

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Re: Clindomycin & C. Diff
« Reply #3 on: April 03, 2019, 07:41:52 PM »
While they are not in the audio range, I do know the frequencies that kill C. Diff. and Mersa in about 4 hours. I had to use the C. Diff. while in the nursing home. An out break in my wing killed several and sent several nurses home. When it was over, they asked how I survived. Every time I felt it coming on, I treated myself with the kill frequency. I have done the same for Staph, Strep, and CMV. The frequency can be found in Hulda Clarks book, "The cure for All Diseases". There are free copies on line for those who wish to look.
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irish

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Re: Clindomycin & C. Diff
« Reply #4 on: April 03, 2019, 10:19:42 PM »
Julie, I am so glad that you brought this up. C. diff is devastating. A neighbor down the road from hubby and me in the country( a few years ago) had an infection and was on 2 antibiotics. He got diarrhea and nausea and thought he had the flu. Went to ER and sent by ambulance to Mpls. and was dead by the time they got him there.

One thing I should mention is that this diarrhea is bloody usually and there is generally mucus and tissue in it. The lining of the colon is destroyed and shed. The diarrhea also can have a really foul odor. Some people describe it as having a "barn" smell. Even if you are on one antibiotic you can get c.diff and with 2 or more antibiotics the chances are even higher. I don't know if taking probiotics prevents it but it sure can't hurt. The c.diff puts out a toxin that causes all the problems.

Thanks again for mentioning this. Also, MRSA is a pest and then some. I have had it at least 4 times and will culture it in my throat on occasion. The interesting thing is that a high percentage of people will have the MRSA periodically and my ENT says you would not believe the number of people that come to the hospital with positive throat cultures who are not sick. The goal is to always wash your hands and for sure watch where you eat, put your hands and go to the bathroom whatn you are out and about. Carry antibacterial wipes in the car with you.

We can't prevent everything, but it pays to be careful and aware cause many people have really bad habits... kills me how many people don't wash their hands in public rest rooms. Thanks. Irish
« Last Edit: April 04, 2019, 05:39:51 PM by irish »

Jenny

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Re: Clindomycin & C. Diff
« Reply #5 on: April 04, 2019, 04:34:38 AM »
I had C-Diff a few years ago. Not fun! I had been on antibiotics. Weird, but it?s cured with another, very strong antibiotic, Vancomycin.
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Judie P

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Re: Clindomycin & C. Diff
« Reply #6 on: April 04, 2019, 03:25:21 PM »
Thank you alll for your kind words.  I am still alive and taking the Flagil.  My general practitioner (who I have to see for everything and then he sends me out to specialists) just got back from his honeymoon and saw my ER saga.  His care provider called me this morning and said he wants to see me in two weeks to see how I am doing.  He is young, but has been studying up on Sjogren's lately and seems to sometimes be better than my rheumy!  LOL

I am on a BRAT diet (banana, rice, apple sauce and toast/herbal tea).  Though I can't stop thinking about dying from this thing, I am also reminding myself that much more people survive than die.  I am keeping hydrated, which is very important.  C. Diff swells up the large intestines and colon, which can then block gas and stools.  So far that is not a problem for me.  My insurance is Medicare and CCHGP, the county hospital here.  They are very up to date in equipment, etc., and are a teaching hospital.  Lots of great nurse practitioners!  The only reason I had to wait 15 hours in ER was because one ambulance after another was coming through with severe situations.  This hospital is one of the best, and oldest, in my area.  While sitting in my hallway bed (beds were hard to find in ER with all the emergencies) I watched them bring in a 6 week double bypass woman, who was going into cardiac arrest.  By the time I left, she was stable.

I will keep you updated.  Love and hugs.
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irish

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Re: Clindomycin & C. Diff
« Reply #7 on: April 04, 2019, 05:46:16 PM »
So glad that you are maintaining at this point. You should start to improve and if you don't or have any change in symptoms please get to ER. I am assuming that you have been maintaining cause you are on oral med and at home. Sometimes IV meds are necessary. Also, years ago they used the IV vancomycin...put it in a syringe or med cup and took it orally ands it helped.

So glad you have good medical facilities. Good luck, I'll be thinking of you. irish

Jenny

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Re: Clindomycin & C. Diff
« Reply #8 on: April 05, 2019, 04:28:14 AM »
Judie, the Flagyl didn?t work for me, so I was put on Vancomycin which worked quickly. There has also been investigation in using stool from a healthy person injected into the colon. Sounds gross, I know. But if it?s a last resort you?ll try anything. Google it.
63 year old female with back, shoulder, neck and knee pain, dry mouth, losing teeth, dry sinuses,Blood test positive for Sjogrens. Fibromyalgia, Osteoarthritis .
Maloxicam, Lisinopril, Norco, misc.vitamins
4 discs in low back fused. Shoulder replaced 2015 & 2017 Need knee replaced.
4 hand surgeries

Deb 27

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Re: Clindomycin & C. Diff
« Reply #9 on: April 05, 2019, 08:18:12 AM »
Judie, sorry you are going through this!!!!! Yes, C. Diff is a very scary infection. Sometimes doctors will give Flagyl along with other antibiotics to prevent C. Diff.

I would try some strong probiotics like VSL #3 or the strongest thing you can get your hands on. Some people try kefir. That helps to repopulate the intestines with good bacteria. 

Stay on the probiotics any time you have to go on antibiotics.


« Last Edit: April 05, 2019, 02:54:03 PM by Deb 27 »
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Judie P

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Re: Clindomycin & C. Diff
« Reply #10 on: April 16, 2019, 04:58:51 PM »
Well, I promised I would keep you up to date and failed.  Ugh.  The Flagyl seemed to help the C. Diff, but it also caused me to have stiff muscles and affect the stenosis in my neck.  I ended up two more times in ER, one for no neck movement and the next day for no movement in neck or upper back, shoulders and arms.  What a nightmare.  I also have hoarseness, and lots of post nasal drip.  See my regular doctor on Thursday.  Another MRI has been scheduled for April 25.  Don't know if the C. Diff is gone yet, either.   :-[
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irish

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Re: Clindomycin & C. Diff
« Reply #11 on: April 16, 2019, 07:35:04 PM »
So sorry that you are having to go through all this. Hopefully it will resolve quickly. Just wondering if the Flagy interactered with and of your other meds. As was mentioned the vancomyin is also used for this and probably some newer drugs that I am not familiar with. They will will be watching over you I would bet.

There is the possibility that this stiffness is rela (spelling) Guianne barre syndrome. My thoughts are with you. Irish