Author Topic: Update: progesterone for dry eyes  (Read 1712 times)

Maria3667

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Update: progesterone for dry eyes
« on: November 27, 2018, 04:04:24 AM »
Hi everyone,

Have I been barking up the wrong tree the whole time? I've been a strong advocate for low dose Dhea (2,5 mgs, preferably sublingual / intravaginal) to increase mouth & eye moisture. Which worked -  until menopause hit me.

Last month my eyes were so painfully infected I was prepared to drink horse pee! Fortunately it didn't come to that as I dug up a scientific paper from 2007 claiming progesterone rubs on the eyelids 2x daily can treat eye inflammation.

I tried testosterone, estriol and Dhea cream, but had never seen progesterone mentioned. When I woke up last Wednesday morning I immediately felt a stark difference. My eyes didn't stick or hurt!

Gradually the improvement amplified; the cornea is finally healing & now I rarely grab eye drops.

Progesterone is plausible, as all hormones dwindle in menopause. But I sure wish I'd known sooner!

« Last Edit: December 23, 2018, 02:43:46 AM by Maria3667 »
51. DES-daughter ('67), Lyme's ('98), GAD ('98), Sjogren's ('03), hypothyroid ('04), endometriosis ('14), osteoarthritis ('16), blepharitis ('18), frozen shoulder ('19). Meds: pilocarpine, T3&T4, 25mg quetiapine, low dose testosterone & progesterone. Allergies: nickle, methylisothiazolinone, latex

Sharon

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Re: Surprise: progesterone increases eye moisture
« Reply #1 on: November 27, 2018, 12:07:09 PM »
I have also suspected that Progesterone is key, but Progesterone cream that I used didn't make a difference for my eyes.
I did only use it at night though.
Maybe I wasn't using the right one?
Which type of Progesterone did you use?
Sjogren's (+ RA?) positive ANA, RNP, RNP-A, APCA salivary gland swelling, dry mouth & eyes,, eyelid swelling & redness, photosensitivity, fatigue, severe joint pain, multiple sensitivities and allergic reactions 
Orencia, Restasis, Paleo Diet, Vit. D & C, Ubiquinol 200mg, Omega 3...

Maria3667

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Re: Surprise: progesterone increases eye moisture
« Reply #2 on: November 27, 2018, 02:00:30 PM »
Hi Sharon,

Like I posted in the paramount study about hormones before, it's probably due to their interaction. Like an orchestra playing together.

As I also take a pinprick of transdermal testosterone, 2.5 mgs of Dhea and a 1/4 tablet 2x weekly of Livial, I suspect progesterone is the missing ingredient (or musical conductor, lol... ).

The brand I use is Pro-Gest (natural progesterone, by Emerita). I apply on upper and lower eyelids at dawn & night. I'm truly amazed at the beneficial effect.

Study: https://iovs.arvojournals.org/article.aspx?articleid=2382585

« Last Edit: November 29, 2018, 02:26:20 PM by Maria3667 »
51. DES-daughter ('67), Lyme's ('98), GAD ('98), Sjogren's ('03), hypothyroid ('04), endometriosis ('14), osteoarthritis ('16), blepharitis ('18), frozen shoulder ('19). Meds: pilocarpine, T3&T4, 25mg quetiapine, low dose testosterone & progesterone. Allergies: nickle, methylisothiazolinone, latex

Sharon

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Re: Surprise: progesterone increases eye moisture
« Reply #3 on: November 27, 2018, 02:15:27 PM »
That's the same one I used  :)
How wonderful that you've found relief!
I think I'll try the cream again with the instructions you suggested.
Sjogren's (+ RA?) positive ANA, RNP, RNP-A, APCA salivary gland swelling, dry mouth & eyes,, eyelid swelling & redness, photosensitivity, fatigue, severe joint pain, multiple sensitivities and allergic reactions 
Orencia, Restasis, Paleo Diet, Vit. D & C, Ubiquinol 200mg, Omega 3...

Deseree

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Re: Surprise: progesterone increases eye moisture
« Reply #4 on: November 27, 2018, 03:13:25 PM »
I've heard some great things about progesterone for dryness, glad it worked for you!
30 year old female. Mildly positive ANA and RF. Positive markers on Early Sjogren's blood test. Negative Ss-A/Ss-B. Dry mouth, nose, throat, and eyes. Currently taking generic Evoxac.

bluegardenia

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Re: Surprise: progesterone increases eye moisture
« Reply #5 on: November 27, 2018, 03:20:53 PM »
do you buy it on amazon?
60,primary sjs, diverticulosis,ibs,atrioventricular blocks 2 degree first type, acid reflux.
omeoprazole, vit c, flack seed, omega 3, b complex, nac,systane ultra, pineapple seeds

Maria3667

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Re: Surprise: progesterone increases eye moisture
« Reply #6 on: November 27, 2018, 03:45:37 PM »
Hi Blue,

Well, it was some time ago. I don't think I got it from Amazon; probably just a regular website.

Good luck!
51. DES-daughter ('67), Lyme's ('98), GAD ('98), Sjogren's ('03), hypothyroid ('04), endometriosis ('14), osteoarthritis ('16), blepharitis ('18), frozen shoulder ('19). Meds: pilocarpine, T3&T4, 25mg quetiapine, low dose testosterone & progesterone. Allergies: nickle, methylisothiazolinone, latex

Sharon

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Re: Surprise: progesterone increases eye moisture
« Reply #7 on: November 28, 2018, 11:07:55 AM »
I ordered it from iherb.
Sjogren's (+ RA?) positive ANA, RNP, RNP-A, APCA salivary gland swelling, dry mouth & eyes,, eyelid swelling & redness, photosensitivity, fatigue, severe joint pain, multiple sensitivities and allergic reactions 
Orencia, Restasis, Paleo Diet, Vit. D & C, Ubiquinol 200mg, Omega 3...

bluegardenia

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Re: Surprise: progesterone increases eye moisture
« Reply #8 on: November 28, 2018, 01:11:51 PM »
thanks Maria and Sharon
60,primary sjs, diverticulosis,ibs,atrioventricular blocks 2 degree first type, acid reflux.
omeoprazole, vit c, flack seed, omega 3, b complex, nac,systane ultra, pineapple seeds

Carolina

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Re: Surprise: progesterone increases eye moisture
« Reply #9 on: November 28, 2018, 03:58:03 PM »
Thank you,Maria,

I just ordered Pro-Gest from Amazon.

Hope I have some relief and I will keep you all posted!

Regards, Elaine
Female-Elaine,76-CVID-pSJS-IC-PN-CAD-Osteoarthritis-COPD-SFN-Knee/Shoulder Degeneration-SIBO-Intertrigo-Act.Purpura-Anemia-Copper Def-Raynaud's-Meniere's-Hiatal Hernia-Achalasia-IVIG Gamunex-Medrol-Gabapentin-Atenolol-Pilocarpine-LDN-Nasonex-Lipitor-Estrogel-B-12-Iron-D-Mannose-NAC-Co-Q10-D3-Omega 3

Maria3667

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Re: Surprise: progesterone increases eye moisture
« Reply #10 on: November 29, 2018, 02:19:02 PM »
You're welcome everyone  ;D.  Hope it pays off for all of us trying this natural progesterone cream.

I forgot to mention that for the first 3 or 4 days I applied it up to 4x daily to get the glands going again. I have now reduced to 2x, but I feel I need 3x (unpractical, because that requires an extra application at lunchtime when I'm at the office wearing eye make up - progesterone eye drops would be easier).

My dryness is exacerbated by quetiapine which I use as an anxiolytic and sleep aid.

Keen to learn your results! Please keep us posted!
« Last Edit: November 29, 2018, 02:24:31 PM by Maria3667 »
51. DES-daughter ('67), Lyme's ('98), GAD ('98), Sjogren's ('03), hypothyroid ('04), endometriosis ('14), osteoarthritis ('16), blepharitis ('18), frozen shoulder ('19). Meds: pilocarpine, T3&T4, 25mg quetiapine, low dose testosterone & progesterone. Allergies: nickle, methylisothiazolinone, latex

Lotus1

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Re: Surprise: progesterone increases eye moisture
« Reply #11 on: December 06, 2018, 04:38:50 PM »
Thanks so much for sharing Maria3667.

I may ask my hormone dr if it can be made up at the compounding chemist.
What strength is the progesterone cream please?

I use natural hrt & my body loves progesterone!!

I'm feeling hopeful......

Lotus1


araminta

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Re: Surprise: progesterone increases eye moisture
« Reply #12 on: December 07, 2018, 03:54:06 AM »
Have any more of you tried this yet?   I'm considering getting the Pro Gest but wondered if there were any more good news stories.
Dry eyes (MGD), nose, mouth, labyrinthitis, rashes, dry skin (occasional eczeme), mouth ulcers, constant but fluctuating fatigue.  Blood tests and Schirmers negative,no Sjogrens dx yet.   Flax oil, multivitamins,  saline nasal spray, Hylo forte, Lacrilube, organic castor oil for eyes, moisturisers.

Maria3667

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Re: Surprise: progesterone increases eye moisture
« Reply #13 on: December 23, 2018, 01:25:14 AM »
Hi Araminta,

Been on a tiny amount of Pro-Gest for 1 month now. The effects are impressive! Eye moisture is almost back to normal  :D

There's 1 snafu: after a year's absence my period returned! How can such a tiny amount (1/2 a green pea) have this effect?

Also, saliva flow & mouth burning have improved!
« Last Edit: December 23, 2018, 02:46:42 AM by Maria3667 »
51. DES-daughter ('67), Lyme's ('98), GAD ('98), Sjogren's ('03), hypothyroid ('04), endometriosis ('14), osteoarthritis ('16), blepharitis ('18), frozen shoulder ('19). Meds: pilocarpine, T3&T4, 25mg quetiapine, low dose testosterone & progesterone. Allergies: nickle, methylisothiazolinone, latex

araminta

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Re: Update: progesterone for dry eyes
« Reply #14 on: December 23, 2018, 03:21:36 AM »
Thanks Maria, very glad you're getting good help with this.   I might give progesterone another go.   I tried it before without much noticeable difference, but never on eyelids.
Dry eyes (MGD), nose, mouth, labyrinthitis, rashes, dry skin (occasional eczeme), mouth ulcers, constant but fluctuating fatigue.  Blood tests and Schirmers negative,no Sjogrens dx yet.   Flax oil, multivitamins,  saline nasal spray, Hylo forte, Lacrilube, organic castor oil for eyes, moisturisers.