Author Topic: How long have you been on Evoxac/Salagen?  (Read 479 times)


  • Newbie
  • *
  • Posts: 44
How long have you been on Evoxac/Salagen?
« on: October 08, 2018, 12:11:06 AM »
I am thinking about asking my doctor to prescribe one of these meds at my next visit and I have a few questions.

Do these become less effective the more you use them? Is it possible to build up a tolerance or "overwork" the glands by constantly stimulating them with meds?

Is there anyone here who has taken them for 10+ years and can report on long term effectiveness, side effects, etc?

I know I keep asking lots of questions on here, I'm just struggling with the symptoms and I'm really scared because none of my doctors have yet been able to suggest a cause. They don't think it's Sjogren's, but I have so many of the symptoms and I just want some relief! Thanks again everyone, you are always so helpful!
30 year old female. Mildly positive ANA and RF. Positive markers on Early Sjogren's blood test. Negative Ss-A/Ss-B. Dry mouth, nose, throat, and eyes. Currently taking generic Evoxac.


  • Hero Member
  • *****
  • Posts: 703
Re: How long have you been on Evoxac/Salagen?
« Reply #1 on: October 08, 2018, 08:50:32 AM »
I have been on Evoxac for more than three years. Still works as well today as when I started.
Sjogren's, lupus, OAB and osteopenia
Rx: Evoxac and Myrbetriq
Vitamins and Supplements: A, B complex, C, D3, E, calcium orotate, magnesium glycinate, D-Mannose, curcumin, fish oil, probiotic


  • Newbie
  • *
  • Posts: 33
  • Also known as Kevin
Re: How long have you been on Evoxac/Salagen?
« Reply #2 on: October 10, 2018, 04:35:41 PM »
Have been on Exovac for 3 or 4 months. It is really helping. As a bonus it has made my eyes less dry as well.


  • Hero Member
  • *****
  • Posts: 764
  • Still cultivating that 'dry' sense of humor...
Re: How long have you been on Evoxac/Salagen?
« Reply #3 on: October 11, 2018, 10:25:49 AM »
Hi Deseree,

I've been on Salagen or generic pilocarpine for 15 years now. I do feel it's become less effective over time, but this is possibly due to the fact that I've entered menopause.

The effectiveness can be enhanced by simultaneous use of hormones (especially dhea, testosterone or estrogen), supplements (curcumine, glucosamine, green lip muscle extract, nigella sativa, etc.) or antibiotics and such.

Basically I couldn't function without it!
« Last Edit: October 11, 2018, 10:49:27 AM by Maria3667 »
51. DES-daughter, GAD, Lyme's ('98), Sjogren's ('03), hypothyroid ('04), osteoarthritis ('16), Blepharitis ('18), bilateral Frozen Shoulder ('19), pilocarpine, thyroid hormones, 25mg quetiapine, low dose testosterone. Endometriosis, cherry angiomas. Allergies: nickle, methylisothiazolinone, latex


  • Newbie
  • *
  • Posts: 31
Re: How long have you been on Evoxac/Salagen?
« Reply #4 on: October 12, 2018, 08:54:24 PM »
2 years on generic evoxac, so far so good.