Author Topic: Hope on the horizon? New study  (Read 286 times)

Sharon

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Hope on the horizon? New study
« on: November 13, 2017, 12:21:37 PM »
Check out this new medication being studied for SS.
Initial results are encouraging:

https://www.novartis.com/stories/discovery/targeting-roots-sjogrens-syndrome

 :) :) :)
Sjogren's (+ RA?) positive ANA, RNP, RNP-A, APCA salivary gland swelling, dry mouth & eyes,, eyelid swelling & redness, photosensitivity, fatigue, severe joint pain, multiple sensitivities and allergic reactions 
Orencia, Restasis, Paleo Diet, Vit. D & C, Ubiquinol 200mg, Omega 3...

Spring

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Re: Hope on the horizon? New study
« Reply #1 on: November 16, 2017, 07:01:14 AM »
Interesting and hopeful, thanks for sharing Sharon!

Sharon

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Re: Hope on the horizon? New study
« Reply #2 on: November 16, 2017, 12:55:04 PM »
Gladly. Hope is important!
Sjogren's (+ RA?) positive ANA, RNP, RNP-A, APCA salivary gland swelling, dry mouth & eyes,, eyelid swelling & redness, photosensitivity, fatigue, severe joint pain, multiple sensitivities and allergic reactions 
Orencia, Restasis, Paleo Diet, Vit. D & C, Ubiquinol 200mg, Omega 3...

Maria3667

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Re: Hope on the horizon? New study
« Reply #3 on: November 20, 2017, 12:35:02 AM »
Hi Sharon,

Interesting study!

But I wonder if it's really targeting our most prominent symptoms such as dry mouth & eyes, because the study claims:

"According to Fisher, score changes reflected improvements in swollen glands, night sweats, fevers, and swollen and painful joints. “These results are fascinating,” he says."

Sure they are fascinating, but could also be symptomatic of dozens of other diseases. I for one, don't typically suffer from night sweats, fevers and swollen joints.... My main problem is oral and ocular dryness.

Anyhow, any study moving closer towards understanding the complications of AI-diseases could eventually benefit us... It's good to have hope.

Thanks for sharing  :)
49, F. Lyme's (1998), Sjogren's (2003), hypothyroidism (2004), osteoarthritis (2016), DES-daughter, GAD. Pilocarpine, natural thyroid hormones, 25mg quetiapine, low dose testosterone, 2.5 mg dhea, supplements. Endometriosis, cherry angiomas, macules. Allergies: nickle, methylisothiazolinone, latex

Sharon

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Re: Hope on the horizon? New study
« Reply #4 on: November 20, 2017, 01:34:17 AM »
Hi Maria, I also found it strange they didn't mention sicca symptoms in the study.
However, I do get everything else they mentioned and would love to get any relief I can from any symptom possible. Perhaps sicca relief will be mentioned in their future studies.
Sjogren's (+ RA?) positive ANA, RNP, RNP-A, APCA salivary gland swelling, dry mouth & eyes,, eyelid swelling & redness, photosensitivity, fatigue, severe joint pain, multiple sensitivities and allergic reactions 
Orencia, Restasis, Paleo Diet, Vit. D & C, Ubiquinol 200mg, Omega 3...

warmwaters

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Re: Hope on the horizon? New study
« Reply #5 on: November 20, 2017, 07:33:30 AM »
There are a variety of patterns to this disease. My worst conditions are the fatigue, pain, brain fog, and neuro damage.  So this is a candidate for my needs, if it proves to be useful.  I wouldn't discard it if it didn't solve sicca.
Primary Sjogrens, dx June 2009, Immunoglobulin deficiency, axial spondylosis arthritis, IBS, autonomic neuropathy
Omeprazone DR 40 mg, mobic 15 mg, Plaquenil, LDN, B1, B6, B12, D, fludrocortisone, gralise, various inhalers

Sharon

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Re: Hope on the horizon? New study
« Reply #6 on: November 20, 2017, 10:48:50 AM »
Same here warmwaters
« Last Edit: November 21, 2017, 01:24:13 PM by Sharon »
Sjogren's (+ RA?) positive ANA, RNP, RNP-A, APCA salivary gland swelling, dry mouth & eyes,, eyelid swelling & redness, photosensitivity, fatigue, severe joint pain, multiple sensitivities and allergic reactions 
Orencia, Restasis, Paleo Diet, Vit. D & C, Ubiquinol 200mg, Omega 3...

Nymph

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Re: Hope on the horizon? New study
« Reply #7 on: November 21, 2017, 03:45:20 AM »
Exciting!
38 y.o. teacher; anti-CCP+, RF+, otherwise seronegative; POTS; Plaquenil, Allegra, Depakote, Neurolink, C, probiotic, multi-V, magnesium, quercetin, NAC, DHEA, fish oil, D3, turmeric, ubiquinol; <3 my neti pot

irish

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Re: Hope on the horizon? New study
« Reply #8 on: Today at 08:41:34 PM »
If they can influence the antibodies they indicate the dryness will be decreased or stopped. Every single symptom he mentioned is part of the autoimmune attack on the body in Sjogrens. There are also a whole bunch more symptoms that many patients may not experience. If they can even scratch the surface in the qwest for cure in Sjogrens it will affect every other autoimmune disease study in one way or another, not to mention cure. The march towards cure is proceding and getting closes. irish