Author Topic: Dry mouth product  (Read 5081 times)

DryGuy

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Dry mouth product
« on: May 07, 2014, 01:07:43 PM »
Has anyone tried aquoral. It's a fairly new dry mouth product. It's considered a medical device with coupons on the website. If anyone has tried it please give a review!

drylady

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Re: Dry mouth product
« Reply #1 on: May 07, 2014, 02:49:25 PM »
Hi Dryguy. Your post is the first I've heard of this product. I googled it and it looks like it requires a prescription. I'm also interested if anyone has tried it. I'm going to ask my rheumy about it next visit.
33 years old. Plaquenil 200mg (2x), Evoxac 30mg (3 x).

machenza

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Re: Dry mouth product
« Reply #2 on: May 07, 2014, 03:01:02 PM »
I saw a study that compared it to mouth wash but have no idea how to get it. Let us know if it can be obtained OTC

Nellie

ohiolady

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Re: Dry mouth product
« Reply #3 on: May 07, 2014, 03:27:03 PM »
Dryguy, haven't tried the product.  I was looking at your meds and think Flexeril would be quite drying.  I took it briefly before Sjogrens and remember it to be drying.  I only took it for a short time.  Just thought I'd mention

Anna
SJS  Hashimoto's   Mild Raynauds  GERD  Gastroparesis
Restasis, Evoxac, Dexilant,  Domperidone, Zofran and Synthroid. Fish Oil, Vit D and B12  R lipoic acid,  Acetyl L Cartnine, Vitamin B1, and The Perfect Food Green and Fruit supplement

Kidney Cancer Survivor   
Female   Age: 62

machenza

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Re: Dry mouth product
« Reply #4 on: May 07, 2014, 06:48:49 PM »
Has anyone tried aquoral. It's a fairly new dry mouth product. It's considered a medical device with coupons on the website. If anyone has tried it please give a review!

I guess that it is like NeutraSal but a different brand. There is another product- OraMoist, Axiomedic, Zurich, but I am not sure how we can get it, and if it is imported in the US. One day, when I finnaly have an appointment with the rheumy (referral is in 34 day now), I will ask if it is available in Japan.

I also found a study on a product called Salinum (without or with chlorhexidine rinse). It is more effective compared to the two above.

Nellie

DryGuy

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Re: Dry mouth product
« Reply #5 on: May 07, 2014, 07:17:17 PM »
Thanks ohiolady, I actually only used it a couple times to help me sleep when this mess first started.  Now I use klonopin to help me sleep if I'm having a hrd time, since it has the rare side effect of increased salivation.  I've been avoiding drying medications like the plague.

The person who told me about aquoral said she tried it and it worked close to 4 hours and even ate with it and still felt it working a little after she was done eating.

ammasgirl

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Re: Dry mouth product
« Reply #6 on: May 07, 2014, 08:32:18 PM »
Dryguy- my mother has used Aquoral- she got an rx for it, although I've seen it listed as an OTC product, so perhaps it is in other countries. I pushed for it after seeing some research, and she thought it helped a little bit. I tried it myself, just to make sure it wasn't too strong, or too offensive tasting, and it wasn't, but it's oil-based, and that's exactly what it feels like. If you're someone who feels relief by rinsing with oils, then it would probably work well for you, because it sprays out a fine mist and also lasts a long time.  My mother did feel like it helped with some of her mouth discomfort, but of course, it doesn't actually produce saliva, so she didn't stick with it.  She's a bit of an all or nothing person, though, so I really thought she should have tried longer as it definitely helped some. IIRC there's kind of a floral taste to it, which isn't great, but not horrible, and I can see how it could be very soothing as long as the oiliness isn't a problem. Good luck.

gemini052377

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Re: Dry mouth product
« Reply #7 on: May 07, 2014, 09:21:44 PM »
Thanks DryGuy for bringing this product to our attention and Ammasgirl for the review.
Mary-Primary Sjogren' s, Hashimoto' s Auto Immune Thyroid, Fibromyalgia, Chronic Fatigue Syndrome, Reynauds, and busy mom of 4 kiddos :)

cccourt1942

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Dry mouth product
« Reply #8 on: May 08, 2014, 07:05:01 AM »
Hi Guy,
    Are you wanting to use this as an alternative or an additive to an Rx?  I am always up for anything.  Am I correct believing this requires a prescription?  (I am asking as here I have to go to EACH specialist for a drug for EACH body area!)  I see so many doctors now I have my application for a handicapped parking permit---just to be able to find a parking place at doctors' offices.  (I don't even believe in these tags!)   Ick.
« Last Edit: May 08, 2014, 12:36:39 PM by cccourt1942 »
Sjogren's, Psoriasis, Hashimoto's, Osteoporosis, Osteoarthritis, Cold hands/feet,  fatigue,  pilocarpine-25 mg , Restasis, Plaquenil, Low dose Prednisone (2-3 mg daily) Xylimelt, Citrucel, Alcon-Naturale, Tears,Omega 3, Vit.D, Caltrate+D3, Fosamax, CoQ10, Zinc, Oxtellar. Levothyroxene

lighthouse33

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Re: Dry mouth product
« Reply #9 on: May 08, 2014, 11:11:44 AM »
Aquoral: lasting dry mouth relief is just a spray away

Dry Mouth Hurts

Do you feel like there is too little saliva in your mouth? Do you have difficulty swallowing? Does your mouth feel dry when eating? Do you have to sip liquids when swallowing dry foods? These are all symptoms related to dry mouth, or xerostomia. Dry mouth can be a serious condition and is caused by a variety of things, including medication use, certain medical conditions, or even the aging process.

Dry Mouth Relief!

Aquoral? can provide relief from the troublesome and often debilitating symptoms of dry mouth caused by diseases, medication use, chemo- or radiotherapy, stress, and aging.

Aquoral delivers fast relief by:

Moistening and lubricating your mouth
Limiting loss of essential water
Protecting against oral inflammation
________________________________________

Aquoral is an FDA approved protective oral spray proven to lessen the effects of dry mouth with an excellent safety profile.

aquoral.com/

Download Aquoral Savings Card

Pay no more than $25 for your first prescription
(Each spray canister of Aquoral lasts up to 2 months when used as directed)
Get up to $40 off subsequent prescriptions

Medicare Patients:

Aquoral is not covered by Medicare. You MAY use this savings card if you are paying the full cash price.

Available by prescription only, Aquoral? is uniquely formulated to moisten dry mouth:

Coats the inside of your mouth
Lubricates the surface of your mouth, tongue, and throat
Protects against further inflammation

Each application lasts up to 4 hours!

aquoral.com/savings_card

Prescribing Information:

aquoral.com/sites/aquoral.com/files/aquoral_prescribinginformation_fnl.pdf

About OGT

The major component?94.4%?of the spray solution is OGT.

Oxidized Glycerol Triester

OGTs are oily lipids that adhere to the surface of the oral cavity forming a protective film over the teeth, gums and tongue. This protects the mouth from mechanical traumas and reduces moisture loss from the oral tissues. OGT is not a saliva substitute or a saliva stimulant and does not contain any pharmacological ingredients.

OGT has been clinically-proven to significantly decrease the feeling of dry mouth in 2 controlled clinical trials. Its efficacy and safety profile was also evaluated in a Cochrane Review.

aquoral.com/page/about-ogt

« Last Edit: May 08, 2014, 11:14:44 AM by lighthouse33 »
Female
Primary Sjogren's, polyneuropathy, endomitriosis, dietary fructose intolerance
Plaquenil, Lyrica, Tramadal, Omeprazole, Fortical, fish oil, flaxseed oil, benefiber, centrum chewable mulitviitamin, caltrate chewable 600 D+minerals, WSN Nerve Support Formula, Align, Biotene Products

lighthouse33

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Re: Dry mouth product
« Reply #10 on: May 08, 2014, 11:12:51 AM »
OGT Clinical Trials

Study 1: use in psychotropic drug-induced dry mouth
In this study, conducted by Mouly et al (2007),1 74 patients who had been on long-term psychotropic drug therapy took part in this 2-week, open-label, randomized, parallel-group study.

Patients were randomized into one of two treatment groups:

37 patients used OGT (Aquoral?)
37 patients treated with artificial saliva substitute (Saliveze?*)

At baseline, 99% of patients complained of mouth dryness during the day, and 66% complained of mouth dryness at night.

The majority of Aquoral? recipients began to experience a sensation of improvement on the second day of treatment which lasted for up to 4 hours after each oral spray. Relief was felt on day 1 in nearly 25% of patients, with more than 50% experiencing improvements by day 2 of treatment

By day 14, patients treated with Aquoral? had experienced a substantial 70% improvement from baseline in dry mouth sensation (p<0.001) as well as improvements in chewing, swallowing, taste and speech, and a reduction in burning sensation. In addition, Aquoral? had significantly better efficacy with respect to mouth dryness, speech difficulties and taste improvement (all p≤0.02) as compared with the artificial saliva substitute.

________________________________________
More than 85% of patients were willing to continue use Aquoral after the study ended
________________________________________

Study 2: management of dry mouth in older patients

In this study, also conducted by Mouly et al. (2007),2 41 patients (28 women and 13 men), with an average age of 84 years, took part in this 2-week, open-label, randomized, parallel-group study. Twenty-two patients received Aquoral and 19 patients received a prescription artificial saliva substitute. Please note that in addition to being older, these study participants were also on an average of 4.2 medications each?and were the classes of medications typically associated with causing dry mouth (e.g., diuretics, antihypertensives, antiarrhythmics, and antipsychotics).

At baseline, 98% of patients complained of mouth dryness during the day, and 76% complained of mouth dryness at night. After 2 weeks of treatment, Aquoral? improved the overall sensation of mouth dryness by 66% (p<0.001 vs. baseline) and was again significantly more effective than the artificial saliva substitute (p=0.001). Aquoral was also significantly better at improving swallowing and speech than the saliva substitute. Relief from symptoms lasted 2-4 hours after Aquoral administration, similar to the duration of relieve observed in the study that evaluation patients with psychotropic drug-induced dry mouth.

Minor adverse events were reported in four patients (9.8%) and included nausea (1 patient in the control group) and unpleasant taste (2 patients receiving the other prescription medication and 1 patient in the Aquoral group).

________________________________________
76% of patients said they would continue using Aquoral after the study ended
________________________________________

Cochrane Review

While not clinical trials, Cochrane Reviews3 are systematic reviews of primary research and look for evidence-based answers to specific questions about healthcare. This review set out to identify effective topical therapies for the relief of the symptom of dry mouth and included both saliva substitutes applied to the oral mucosa as liquids, gels or sprays and saliva stimulants such as lozenges, chewing gum, or toothpastes. In this review, 36 randomized controlled trials involving 1597 participants were evaluated. While no strong evidence supporting one type of intervention over another emerged, this review found that OGT (Aquoral) shows evidence of effectiveness compared to an electrolyte sprays?an observation that provides independent confirmation and further support for the results of the two clinical trials described earlier.

References:

1.   Mouly SJ, Orler J-B, Tillet Y, et al. Efficacy of a new oral lubricant solution in the management of psychotropic drug-induced xerostomia. A randomized, controlled trial. J Clin Psychopharmacol 2007;27(5):437-443.
2.   Mouly SJ, Salom M, Tillet Y, et al. Management of xerostomia in older patients. A randomised controlled trial evaluating the efficacy of a new oral lubricant solution. Drugs Ageing 2007;24(1):957-65.
3.   Furness S, Worthington HV, Bryan G, Birchenough S, McMillan R. Interventions for the management of dry mouth: topical therapies. Cochrane Database of Systematic Reviews 2011;12. Art. No.: CD008934. DOI: 10.1002/14651858.CD008934.pub2.

aquoral.com/page/ogt-clinical-trials





Female
Primary Sjogren's, polyneuropathy, endomitriosis, dietary fructose intolerance
Plaquenil, Lyrica, Tramadal, Omeprazole, Fortical, fish oil, flaxseed oil, benefiber, centrum chewable mulitviitamin, caltrate chewable 600 D+minerals, WSN Nerve Support Formula, Align, Biotene Products

cccourt1942

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Re: Dry mouth product
« Reply #11 on: May 08, 2014, 12:38:48 PM »
Lighthouse is a beacon of..................LIGHT!  Thx for posts.   :D
Sjogren's, Psoriasis, Hashimoto's, Osteoporosis, Osteoarthritis, Cold hands/feet,  fatigue,  pilocarpine-25 mg , Restasis, Plaquenil, Low dose Prednisone (2-3 mg daily) Xylimelt, Citrucel, Alcon-Naturale, Tears,Omega 3, Vit.D, Caltrate+D3, Fosamax, CoQ10, Zinc, Oxtellar. Levothyroxene

lighthouse33

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Re: Dry mouth product
« Reply #12 on: May 08, 2014, 01:49:03 PM »
I was curious about the price so I found a quote at HealthWarehouse.  Then I found the Aquoral Assistance Program at the Bureau of Prescription Health.  Don?t know whether this is legit or not?

$106.25 at HealthWarehouse ? 40 ml Bottle of Aqualor Artificial Saliva Spray ? Prescription Required

Bureau of Prescription Health

freemedicine.com/medlist/Aquoral.shtml

INTRODUCING: AQUORAL ASSISTANCE PROGRAM

Want to save even more? You may be able to get Aquoral FREE with the Aquoral Assistance Program.

Are you worried about how to pay for Aquoral? How many of your other medicines can you not afford?

Take a deep breath and relax a bit. Don't go another day worried about how you are going to pay for Aquoral or your other medications. We've helped thousands of Americans receive their medication at little or no cost, and we can help you too.

Is Aquoral really on a free program? Yes, Aquoral is available on a free or low cost program! Once approved to receive Aquoral, approval is for one year. Reapply year after year for increased savings! It only costs $10.00, once, per prescription, to apply. That is all! The registration fee is non-refundable. If you have questions or need help, you can call us M-F, 7am to 6pm CST at 1-573-996-3333.

HOW MUCH CAN YOU SAVE WITH THE AQUORAL ASSISTANCE PROGRAM

Drug   Quantity/Month   Avg. Yearly Price   Application Fee   Avg. Yearly Savings*

Aquoral   6   $7,199.16   $10.00   $7,189.16
Aquoral   5   $5,999.28   $10.00   $5,989.28

Would you like to save up to $5,989.28 per year, or more? The application process is quick and easy! Upon approval BRAND NAME prescription drugs are either mailed directly to your home, doctor's office or a voucher is sent to you that you can redeem at your local pharmacy. The quantity, eligibility criteria, and dispensing policy varies from drug to drug.

With 54,000 medicines available through free or low cost programs, you should apply for all of the medications you cannot afford. You can save a fortune on your prescriptions, utilizing this approach. Once you are enrolled, it is typically for a year.

Apply for Aquoral and all the other medicines you cannot afford to pay for out-of-pocket.

You can apply online, right now. It's safe, secure, fast and easy.
You can apply over the telephone by calling us at (573) 996-3333. Or, you can download an application and mail it in.

With over 54,000 meds & 800 programs, there is no exact number for income eligibility. Eligibility varies from drug to drug and program to program. Even if the applicant makes more than any program states, that can be appealed on a case-by-case basis. The key guideline is: if you cannot afford to pay for any medications out-of-pocket, you should apply. The worst case scenario is you get a "no" answer, and that can be appealed. It is very rare that we can't help save way more than the $10.00 registration/research fee paid.
Female
Primary Sjogren's, polyneuropathy, endomitriosis, dietary fructose intolerance
Plaquenil, Lyrica, Tramadal, Omeprazole, Fortical, fish oil, flaxseed oil, benefiber, centrum chewable mulitviitamin, caltrate chewable 600 D+minerals, WSN Nerve Support Formula, Align, Biotene Products

stillinshockwithsjogrens

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Re: Dry mouth product
« Reply #13 on: May 09, 2014, 12:43:29 AM »
Interesting information, thank you for sharing, Dry Guy.  I'm seeing my Dentist next week and will ask for an RX.  It's another expensive RX.  At least Evoxac went generic!

I'll report my experience with this product next week.

markt

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Re: Dry mouth product
« Reply #14 on: May 17, 2019, 11:45:12 AM »
Thread revival!

Any updates on folks using Aqua Oral? 

I have an Rx, but have not pursued filling it.  Just wanted to reach out and learn a bit more from everyone here.

Mark