Feb. 1st I began 200 mg. (1 pill) a day of the brand name Plaquenil. Three months later in early May the back of my head began itching. It is STILL causing me grief. Then 3 weeks after the back of my scalp began itching, my upper left shoulder broke out in a bumpy, itchy rash. It looks like miniature hives. My husband prescribed Triamcinolone Cream and this has greatly helped. However, after my left shoulder cleared up, it broke out again terribly 2 weeks later.
My local rheumy feels that if it were related to Plaquenil that my whole body would be itching. However, a dermatologist friend strongly disagrees and said that a drug reaction can cause localized itching.
I tried switching to the generic (Hydroxychoroquine) 1 week ago to see if it would help. Dr. Vivino told me that if I have problems with one, then to try switching to the other. 3 days after trying the generic, my OTHER shoulder broke out in this itchy mess. Now, BOTH shoulders have areas that look like they have miniature hives, along with this incessantly itchy scalp. Also, yesterday a little itchy spot broke out on my abdomen. So....the generic seems to be worse. After 3 and 1/2 months, these itchy areas just aren't going away. It is not due to dry skin.
For those of you with itchy skin due to the Plaquenil, did your Dr. make you get off of it or try reducing the dose? I am only on 200 mg now. Have any of you had itching that never resolved on the Plaq? This is just getting SO annoying, yet I really need to be on this for my severe case of Sjogren's and gastroparesis. Thanks for your input.