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Sjogrens Topics => Neurological Connections => Topic started by: Spring on July 11, 2016, 01:02:25 PM

Title: Sjogren's Syndrome and Neurological Complications
Post by: Spring on July 11, 2016, 01:02:25 PM
What is Sjogren's Syndrome?
by Billie/Care, co-founder of Sjogren's World

Sjogren's Syndrome is a chronic, slowly progressive autoimmune disease that affects the "exocrine" (moisture producing) glands of the body. It is classified as a "connective tissue disease." Some other types of connective tissue diseases are: Lupus, Scleroderma, and Rheumatoid Arthritis. Ninety percent of those afflicted with SS are women. Sjogrens can accompany other autoimmune diseases, most frequently seen in conjunction with Rheumatoid Arthritis. When it is found with another connective tissue disease, it is called "secondary sjs."

Sjogren's Syndrome is classified as "primary sjs" when no other connective tissue disease is present. Sjogren's Syndrome causes dry eyes, dry mouth, and it can also affect other major organ systems. Uncommonly, it can affect the central nervous system.

Neurological complications
Can affect the PERIPHERAL nervous system, and rarely, the CENTRAL nervous system.
Peripheral Nerves

Symptoms of peripheral nerve involvement:
Carpal tunnel syndrome, this can cause "pins & needles" sensations in the wrist. Pain can be associated with this and the pain is often worse at night

Trigeminal Neuralgia can cause an "electric shock" type pain in the face along the "fifth cranial nerve." The pain can become acute.  There can also be some sensory loss in the face.

Sensory Neuropathy, can occur and may cause: sensory loss, ataxia (difficulty walking) and pain.

Central Nervous System

Multiple Sclerosis type symptoms, including, but not limited to: fatigue, difficulty walking, numbness and tingling, bladder and bowel problems, burning pain, difficulty with balance, disorders of position sense, trigeminal neuralgia, optic neuritis, and "stroke" like symptoms.

Treatment for Neurological Problems
Treatment for neurological symptoms associated with Sjogren's Syndrome may include:


Tests used to diagnose neurological problems ssociated with Sjögren's Syndrome (a partial list)


Bibliography:
"The Moisture Seekers" Newsletters

THE MERCK MANUAL, Sixteenth Edition, 1994 pages 1313-4

Principals of Internal Medicine, Isselbackes, 1994, pages 1662-1664

Physicians Guide to Rare Diseases, 1992 pages: 953-954

An excellent explanation of "Nervous System manifestations" in Sjogrens can be found here: Check under Clinical Manifestations, "Extraglandular (systemic) features" at the following  Rheumatology site: RHEUMATOLOGY